The Full Story


You’ve come to the right place for all the research you need to back up why medical transition is no place for a gender-questioning child! Gender dysphoria may not be permanent, with much evidence to support that the feeling may ebb and flow, including the existence of desisters and detransitioners. We need to recognize this fact and proceed accordingly.  



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If you find this page useful, you'll also want to see the Studies page of The Society for Evidence Based Medicine





TReVoices is committed to helping you learn the facts and reality so you can impart that knowledge to your child and make the best medical decisions for your family. We have included as many peer-reviewed articles as possible as well as links to unbiased and balanced outlets. Sometimes the evidence is in the lack of it - not enough studies have been done or properly conducted. Much of the evidence is also unclear because studies were conducted on childhood-onset gender dysphoria and may not be applicable to adolescent-onset gender dysphoria. Of particular note, very few good, reliable studies have been conducted at all about detransitioners, so there is very little information about them - one way or the other.


Ideal studies would have controls, be conducted over long periods of time (ideally 8-10+ years), with a small enough loss to follow up, unflawed study instruments, unflawed analysis, and cohorts relevant to the patients seeking care. Unfortunately, much of the available evidence so far appears to be of low quality and unreliable, frequently with huge losses to follow up, thereby introducing massive uncertainties.

(with thanks to Loving Mum for the research assistance)

Puberty Blockers

Sweden Ends the Use of Puberty Blockers for <16 - May 5, 2021 - Link


UK analysis shows in every category that evidence is very low, including impact on GD, mental health, body image, global functioning, psychosocial functioning, cognitive functioning, bone density and adverse effects - October 2020 - Link

Dutch protocol is no longer being used as originally designed - 2/21/21 - Link

Another Dutch researcher also alarmed at misuse of protocol - October 2020 - Link

UK High Court rules puberty blockers experimental - 12/1/20 - Link

Caution warranted with puberty blockers - October 2020 - Link

Lupron is a category X drug - Link

Increased possible mental health complications - June 3, 2020 - Link

Lasting health problems seem likely - February 2, 2017 - Link

Almost always a one-way ticket to hormones - December 11, 2020 - Link

No or little psychological benefit - July 2019 - Link

By puberty, the majority of child-onset GD sufferers cease to want to transition - 2018 - Link

PBs may lead to osteoporosis - April 2021 - Link


UK analysis finds limited evidence for the effectiveness and safety of gender-affirming hormones in children and adolescents with GD, with all studies being uncontrolled and observational  and all outcomes of very low certainty - October 2020 - Link


Bone density issues - 2019 - Link

Higher risk for blood clots - 2/21/21 -  Link

Higher risk for heart disease - April 2019 - Link

Much reduced chance for lifelong sexual pleasure - November 16, 2017 - Link

Possible liver damage - November 18, 2016 - Link

Increases likelihood of sterility and infertility - June 2016 - Link

Not reversible - December 2020 - Link

Bias, not evidence, dominates WPATH “standards of care” - October 1, 2019 - Link

Long-term use may cause vaginal atrophy - April 2013 - Link

Mental health quality does not seem to improve in a statistically significant way - 2016 - Link

The Mayo Clinic's list of side effects - 2021 - Link

May cause brain to prematurely age - March 25, 2021 - Link

More high-qualities studies are needed, particularly for adolescent-onset GD/Endocrine Society and WPATH provide "practice guidelines" (not standards of care) - March 2021 -  Link 

Mental Health

Medical transition does not seem to improve mental health outcomes - 8/1/20 - Link

Suicide facts and myths - Link

Puberty blockers seem to provide no psychological benefit - July 2019 - Link

Puberty blockers appear to increase mental health complications - June 3, 2020 - Link

Transition surgery seems to increase suicide risk long-term - February 2011 - Link

Puberty blockers do not appear to alleviate negative thoughts - 2021 - Link 

Kids with GD seem to have higher rates of psychiatric and  neurodevelopmental conditions - 2018 - Link 

Many remain highly distressed/suicidal after transgender surgery - 2004 - Link

Many Human brain does not fully mature until around age 25 (studies at end of article) - July 2021 - Link

Gender Dysphoria

Rapid-Onset Gender Dysphoria (ROGD) first named in peer-reviewed study - March 19, 2019 - Link

Whatever it's called, "ROGD" describes a new type of teenage-onset gender dysphoria - August 9, 2021 - Link

Gender dysphoria is now almost always conflated with transgenderism - January 24, 2018 - Link

More resources from Gender Dysphoria Alliance - Link

Possible link with polycystic ovary syndrome (PCOS) - June 2012 - Link

The End of Gender by Debra Soh - August 2020 - Link

Clinicians pressured to quickly diagnose and medicalize GD - April 2021 - Link



One Size Does Not Fit All: In Support of Psychotherapy for Gender Dysphoria - 10/21/20 - Link

Finland prioritizes psychotherapeutic treatments for youth with GD - 2020 - Link

Book by two experts describes therapeutic options for GD - February 2021 - Link

Activists conflating ethical psychotherapy with conversion therapy - November 16, 2020 - Link

Framing transitioning and the need for deep research - December 24, 2020 - Link

Freedom to Think: The need for thorough assessment and treatment of gender dysphoric children - July 21, 2020 - Link

Is it ethical to affirm when medicalization is on the line? - July 30, 2021 - Link


Gender reassignment surgery may shorten lives - March 2016 - Link

Does not seem to improve mental health outcomes - August 2020- Link

Much reduced change for lifelong sexual pleasure - November 2017- Link

Can minors consent to double mastectomy of health breasts ("top surgery")? - March 2021- Link

Yes, girls as young as 13 are having double mastectomies of healthy breasts - May 2018 - Link

Vaginoplasty complications include fistulas, necrosis, and prolapses - March 2021 - Link

Phalloplasty complications high, with low mental health benefits - March 2021 - Link



Correlation between autism and gender dysphoria - August 7, 2020 - Link

Possible correlations between ADHD and gender dysphoria - 2020 - Link - 2014 - Link

Most kids with gender dysphoria will grow up to be gay - 2012 - Link

Anecdotal evidence shows link between giftedness and GD - 2017 - Link

Case study of link between GD and OCD - April 2016 - Link

Links with anxiety, depression, trauma, abuse, and autism - April 2021 - Link

Possible causes of gender dysphoria - Link

Follow the Money

Transgender medicine provides profitable business opportunities - July 2018 - Link

Many transgender researchers have conflicts of interest - November 2017 - Link

Planned Parenthood now makes its money from hormones - February 2021 - Link

Lupron is a money maker when prescribed to kids - February 2020 - Link

Transgender marketing is big business - March 2021 - Link

The business model of youth transitioning - March 21, 2021 - Link

Prominent PB-prescribing doctor's conflict of interest - Aug 2020 - Link

Sex-reassignment surgery is a growing industry - March 2020 - Link

Amazon push into pharma might explain bans of certain books - April 2021 - Link


Journalists are being manipulated - April 2021 - Link

Gender dysphoria drug market forecasted to be huge - October 2020 - Link

The Marketing Funnel of Gender Ideology - June 2021 - Link

UK Resources
International Resources

Genspect - a voice for parents of gender-questioning kids - Link

Gender Dysphoria Support Network - with a huge list of resources - Link

Parents of ROGD Kids - Link

Post-Trans - Link

Detrans Voices - Link

Gender: A Wider Lens (podcast) - Link

Gender-Critical Support Board - Link


The pressing need for research and services for gender desisters and detransitioners - 11/1/20 - Link

A Typology of Gender Detransition and Its Implications for Healthcare Providers - 1/10/21 - Link

Many transgender researchers are suppressing research on detrans/desistance - 2018 - Link

88% of prepubescent boys will desist - March 29, 2021 - Link

Detransitioner's testimonies require  rethink of GD - February 2021 - Link

Detransition-Related Needs and Support: A Cross-Sectional Online Survey - April 30, 2021 - Link

Media/Social Media

What the media gets wrong on gender reassignment - June 2021 - Link


Referrals to gender clinics down in Sweden after mainstream media reports - February 20, 2020 - Link

The role of the internet - February 26, 2021 - Link

Irreversible Damage by Abigail Shrier - July 2020 - Link

The general role of influencers on social media - February 26, 2019 - Link

USA Resources